Scientific Program
| Thursday, November 16 | Friday, November 17 | Saturday, November 18 | Sunday, November 19 |
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| Pre-Conference Workshops | View Program | View Program | View Program |
Friday, November 17, 2017
| 8:00-8:30 | Morning Coffee | Exhibition Area | |
Opening Session |
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| 8:30-8:45 | Welcome and Announcement of the “Young Investigator Award” David F. Albertini, USA and Norbert Gleicher, USA |
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| 8:45-9:15 | The “Breaking News” Lecture: Gene correction in human gametes and embryos for the prevention of heritable diseases? Shoukhrat Mitalipov, USA |
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Session 1: The Future of Assisted Reproduction IChairs: Norbert Gleicher, USA and David F. Albertini, USA |
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| 9:15-9:45 | Tolerating uncertainty – The next medical revolution Richard Martin Schwartzstein, USA |
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| 9:45-10:15 | The self-correcting embryo David F. Albertini, USA |
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| 10:15-10:45 | Imaging follicle maturation in 3 dimensions Diana Laird, USA |
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| 10:45-11:15 | Rejuvenation and expanding life spans by inducing epigenetic changes Juan Carlos Izpisua Belmonte, USA |
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| 11:15-11:35 | Coffee Break | Poster Viewing in the Exhibition Area | |
Session 2: Successful Reproduction is Tolerance DependentChairs: Vitaly Kushnir, USA and David Barad, USA |
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| 11:35-11:55 | Induction of tolerance pathways for establishment and maintenance of pregnancy Norbert Gleicher, USA |
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| 11:55-12:25 | Does the importance of microchimerism for long-term tolerance of organ transplants potentially also apply to tolerance of the fetal semi-allograft? William J. Burlingham, USA |
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| 12:25-12:55 | Pre- and peri-implantation factors involved in inducing tolerance (ignorance) during mammalian gestation Danny Schust, USA |
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| 12:55-1:10 | Get your lunch “to go” | |
Lunch Break Debate – Bring your lunchChair: Norbert Gleicher, USA |
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| 1:10-2:10 | Preimplantation Genetic Screening in association with IVF is: Useful in improving IVF outcomes James A. Grifo, USA Does not improve IVF outcomes and may actually impair them Raoul Orvieto, Israel |
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Session 3: PARADIGM CHANGE I: Polycystic Ovary Syndrome (PCOS), a Multi-Etiological Epigenetic Syndrome?Chairs: Neeta Singh, India and Raoul Orvieto, Israel |
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| 2:10-2:40 | Bilateral nodular adrenal hyperplasia, a possible mechanism for hyperandrogenism in young women with PCOS Constantine A. Stratakis, USA |
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| 2:40-3:00 | Ontogeny of the new hypo-androgenic PCOS phenotype Norbert Gleicher, USA |
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| 3:00-3:30 | Translational insights into PCOS from animal models Daniel Anthony Dumesic, USA |
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| 3:30-4:00 | Coffee Break | Poster Viewing in the Exhibition Area | |
Session 4: The Future of Assisted Reproduction IIChairs: Juan Carlos Izpisua Belmonte, USA and David F. Albertini, USA |
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| 4:00-4:30 | Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations Shoukhrat Mitalipov, USA |
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| 4:30-5:00 | Exchanging the nuclear and mitochondrial human genome Dietrich M. Egli, USA |
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| 5:00-5:30 | Germline editing and how it was “unmade” in the U.S. Eli Y. Adashi, USA |
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| 5:30-6:00 | The ovarian function of the FMR1 gene Lisa Pastore, USA |
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| 6:00-7:00 | Welcome Reception | Exhibition Area | |
Saturday, November 18, 2017
| 8:00-8:30 | Morning Coffee | Exhibition Area | |
Session 5: Quintessential Questions in Assisted ReproductionChairs: Eli Y. Adashi, USA and Aaron J.W. Hsueh, USA |
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| 8:30-9:00 | 3-D printed mouse ovaries producing healthy offspring Teresa K. Woodruff, USA |
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| 9:00-9:30 | Ovarian follicle imaging and activation Aaron J.W. Hsueh, USA |
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| 9:30-10:00 | Gamete reconstitution in vitro Katsuhiko Hayashi, Japan |
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| 10:00-10:30 | Should PGS be used in older women? Nigel E. Pereira, USA |
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| 10:30-10:50 | Coffee Break | Poster Viewing in the Exhibition Area | |
Session 6: PARADIGM CHANGE II: Preventing Rather Than Treating Female InfertilityChairs: Neeta Singh, India and Kara Goldman, USA |
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| 10:50-11:20 | The physiology of ovarian aging David F. Albertini, USA |
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| 11:20-11:50 | Can we prevent female infertility through proactive screening programs? Vitaly A. Kushnir, USA |
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| 11:50-12:20 | How realistic an option is fertility preservation in preventing future infertility? David H. Barad, USA |
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| 12:20-12:50 | Eggs and sperm from buccal smears? Eli Y. Adashi, USA |
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| 12:50-1:15 | Get your lunch “to go” | |
Lunch Break Debate – Bring your lunchChair: David H. Barad, USA |
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| 1:15-2:30 | How important is the implantation window? Absolutely important Carlos Simon, Spain Relatively unimportant David F. Albertini, USA |
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Session 7: PARADIGM CHANGE III: Avoiding in IVF Practice “Fashions of the Moment”Chairs: Carlos Simon, Spain and Vitaly A. Kushnir, USA |
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| 2:30-2:50 | Does mild stimulation make any sense? Raoul Orvieto, Israel |
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| 2:50-3:10 | Is there any reason for embryo banking but to artificially inflate outcomes? Vitaly A. Kushnir, USA |
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| 3:10-3:30 | Are all-freeze cycles, followed by frozen-thawed embryo transfer cycles really improving IVF outcomes? Andrea Weghofer, Austria |
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| 3:30-3:50 | Manual or automated embryology? Norbert Gleicher, USA |
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| 3:50-4:20 | Coffee Break | Poster Viewing in the Exhibition Area | |
Session 8: PARADIGM CHANGE IV: Reading the Medical Literature with Appropriate ScepticismChairs: Andrea Weghofer, Austria and Raoul Orvieto, Israel |
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| 4:20-4:40 | Minimal evidence required before introduction of treatments to routine clinical practice: Is there a responsibility for medical journals? Nancy C. Chescheir, USA |
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| 4:40-5:00 | Advantages and risks of RCTs David H. Barad, USA |
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| 5:00-5:20 | Why in IVF outcome reporting based on “intent to treat” is essential Vitaly A. Kushnir, USA |
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| 5:20-5:40 | The journal editors’ responsibilities David F. Albertini, USA |
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Sunday, November 19, 2017
| 8:30-9:00 | Morning Coffee | |
Session 9: Ovarian PhysiologyChairs: David L. Keefe, USA and Zeev Shoham, Israel |
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| 9:00-9:30 | How important is telomere attrition for female infertility? David L. Keefe, USA |
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| 9:30-10:00 | Preserving female fertility during chemotherapy Kara Goldman, USA |
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| 10:00-10:30 | What is an old follicle? Pasquale Patrizio, USA |
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| 10:30-11:00 | The importance of age-appropriate timing of ovulation induction David H. Barad, USA |
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| 11:00-11:30 | Coffee Break | |
Session 10: Quick Updates on the “Most Interesting” Presentations at the 2017 ESHRE and ASRM Meetings and Still Unpublished DataChairs: Pasquale Patrizio, USA and Norbert Gleicher, USA |
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| 11:30-11:50 | First results from ESHRE’S ESTEEM trial of PGS by polar body biopsy David H. Barad, USA |
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| 11:50-12:10 | Bone marrow-derived stem cells to treat Asherman’s syndrome Carlos Simon, Spain |
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| 12:10-12:30 | 2014-2016 IVF outcomes with autologous oocytes in women ages 43-48, including the oldest so-far delivery in the world Norbert Gleicher, USA |
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| 12:30-1:00 | Closing Lecture: New experimental insights into establishments of the ovarian reserve and their clinical implications Humphrey Yao, USA |
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Closing RemarksNorbert Gleicher, USA |
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